A database system of Antiparasitic Drugs with potential Anti-tumor properties (ADA)
Project
name：A database system of Antiparasitic Drugs with potential Anti-tumor properties (ADA)
BuildTime：2024-06-22
Mark
Cancer is the second leading cause of death in the world today. Drugs are essential in cancer treatment, and the development of new anti-tumor drugs is still a top priority. Drug repurposing refers to the strategy of developing new therapeutic uses for drugs that are already on the market or in clinical research. This method can reduce the time and money investment in drug research, and ensure the safety of drugs. There is a close relationship between parasite infection and cancer, and pathogenic parasites are considered to be one of the causes of human cancer. In addition, some antiparasitic drugs and anticancer drugs have the same target proteins, such as tubulin, CDKs, TGR enzyme, etc. Therefore, it is a feasible solution to repurpose existing antiparasitic drugs for anti-tumor use. The database collected the research information of antiparasitic drugs in cancer treatment in recent years, including the molecular structure information of drugs, drug action mechanism, and the toxicity evaluation data of drugs in colorectal cancer, breast cancer, pancreatic cancer and other cancer cell lines, with a total of 267 entries. It can provide data support for the repurposing of antiparasitic drugs and assist in the development of anti-tumor drugs.
