A database system of Psychotropic Drugs with Anti-tumor properties (APA)
Project
name：A database system of Psychotropic Drugs with Anti-tumor properties (APA)
BuildTime：2024-07-02
Mark
Cancer is one of the leading causes of death worldwide. The latest statistics show that cancer accounts for more than 20% of all deaths, and cancer has become a major health threat worldwide. In the face of this challenge, the development of new anticancer drugs is particularly important. The cost of developing a new drug is estimated to be around $1 billion, and it takes an average of 10 years from discovery to market. Therefore, compared with traditional drug development, repurposing an already approved drug for a variety of diseases is a very time-saving and cost-effective method. Approved drugs that have been tested for safety, such as psychotropic drugs that have almost no negative effects on the human body, making them a viable option for treating cancer. Recent studies have also revealed the potential of psychotropic drugs in the anti-tumor field, often by mechanisms including antiproliferation effects related to cell cycle regulators, mitochondria and Ca2+-mediated cell apoptosis, Fas death receptor-mediated cell apoptosis, and PI3K/AKT/mTOR signaling pathways. The database collected the research content of psychotropic drugs in cancer treatment in recent years, including the information such as molecular structure, targets, cell toxicity. A total of 231 entries were included, which provided abundant data support for scientific researchers and promoted anti-tumor research.
