In order to integrate the data resources and results of the research on isothiazolinones in medicine and to promote the related research, literature review and information extraction and analysis were carried out, so as to construct a target database of isothiazolinones, which serves as an auxiliary tool to screen numerous isothiazolinones and converge their core information, including the systematic target analysis, activity analysis, and mechanism study, etc., and Thus, it provides a research basis for the development of antitumor drugs, reduces the cost of developing tumor drugs, and improves the survival rate of tumor patients. To a certain extent, this database can promote the innovation and development of new drugs, help improve the efficiency of R&D, reduce the cost of procurement and testing, and thus realize sustainable research.