In today's medical research and development field, accurate and efficient data support has become the key to promoting innovation. Medical intermediates are some chemical raw materials or chemical products used in the process of drug synthesis, which can effectively promote the process research and development process of innovative drugs and generic drugs, and some key intermediates may become the key factors restricting the process development. Medical intermediate compound database as an auxiliary tool through the screening of many leading medicine intermediate compound and gather its core information, including the system target analysis, activity analysis and mechanism research, etc., to provide research basis for anti-tumor drugs, reduce the cost of development of tumor drugs, improve the survival rate of cancer patients. So far, the database includes 81 kinds of lead medicine intermediate compounds, including the targets of receptors, enzymes, ion channels, transporters, immune system and genes, as well as the analysis of AGS, HCT116, Hela, PANC-1, PA, MPA, A549, SMMC7721 and other cancer cells. To some extent, the database can promote the innovation and development of new drugs, help improve the efficiency of research and development, reduce the cost of procurement and testing, so as to achieve sustainable research.