Pathogenic bacteria are microorganisms that can cause disease, also known as pathogenic microorganisms, including bacteria, viruses, spirochetes, rickettsia, chlamydia, mycoplasma, fungi and actinomycetes. In the survival and development of human beings, the emergence of pathogenic bacteria has caused a series of diseases, such as infection, typhoid fever, tuberculosis and so on. However, with the deepening of research on anti-pathogenic factors, the number of drugs used to treat various bacterial infections or diseases caused by pathogenic microorganisms has gradually increased. In order to integrate the data resources and results of numerous studies and promote comparative studies, literature review and information extraction and analysis were carried out, thereby constructing a factor knowledge base for antagonizing pathogenic bacteria to assist research on antagonizing pathogenic bacteria and treating related diseases, covering The name, molecular mass, molecular formula, CAS number, source, class, mechanism of action, minimum inhibitory concentration, antibacterial spectrum, adverse reactions, references and corresponding links of antibacterial factors are listed. This interface supports the query function of the content of the above anti-pathogen factors. Therefore, this knowledge base will contribute to further research on the related factors of ant-pathogenic bacteria and the treatment of diseases caused by them, and promote the screening strategy of antibacterial factors.